Clinical Research

22+ Peer-Reviewed
Genomics Insights.

Leading publications in Genomics & Foundation Models, 2026. Real-world validated methods for Alzheimer's disease reversal and therapeutic design.

AAAI ICLR NeurIPS ELLIS AI4X-AC

Clinical & Systems Biology Research

Peer-reviewed publications demonstrating our expertise in multi-omic foundation models and therapeutic intervention planning.

22+
Papers
4
Oral Presentations
5
Venues
r>0.99
Validated
2026 29 papers
Genomics & Foundation Models, 2026
Genomics & Perturbation Biology ↗ WORKSHOP
Hierarchical Disease-State Generators for Neurodegenerative Genomics: A Benchmark for Multi-omic Intervention Modeling
David Scott Lewis, Enrique Zueco
NeurodegenerationGenomics
Genomics & Perturbation Biology ↗ WORKSHOP
Toward Generative Virtual Cells: Simulating Cellular Response to Therapeutic Perturbations
David Scott Lewis, Enrique Zueco
Virtual CellsPerturbation Modeling
Computational Systems Biology ↗
Reinforcement Learning for Optimizing Alzheimer's Disease Treatment Timing and Multi-Scale Dosing
David Scott Lewis, Enrique Zueco
Alzheimer'sTreatment Optimization
Computational Systems Biology ↗ ORAL
Causal World Models for Multi-Scale Alzheimer's Disease Progression and Pharmacologic Reversal
David Scott Lewis, Enrique Zueco
Alzheimer'sCausal Models
Neuro-Symbolic Reasoning ↗
Active Causal Hypothesis Testing for NAD+-Centered Alzheimer's Disease Reversal
David Scott Lewis, Enrique Zueco
Alzheimer'sNAD+ Metabolism
Neuro-Symbolic Reasoning ↗ ORAL
Latent-Implicit Thinking with Verified Outputs for Reliable Biomedical Discovery
David Scott Lewis, Enrique Zueco
Biomedical DiscoveryVerifiable Reasoning
Neuro-Symbolic Reasoning ↗ ORAL
Autoformalizing Biomedical Text into Verified Knowledge Graphs for Alzheimer's Disease
David Scott Lewis, Enrique Zueco
Alzheimer'sKnowledge Extraction
Genomics & Foundation Models ↗
Prioritizing NAD+-Enhancing Therapeutic Analogs for Alzheimer's via Multi-Objective Bayesian Optimization
David Scott Lewis, Enrique Zueco
Alzheimer'sLead Optimization
Genomics & Foundation Models ↗
Agentic Active Causal Discovery for Closing the Genomic Experimental Loop in Alzheimer's
David Scott Lewis, Enrique Zueco
Alzheimer'sExperimental Design
Genomics & Foundation Models ↗
Uncertainty-Aware Biomarker Discovery for Alzheimer's Reversal via Conformal Prediction
David Scott Lewis, Enrique Zueco
Alzheimer'sBiomarkers
AI in Drug Discovery (AIDD), 2026
AAAI-26 · AIDD ↗ ORAL
Agentic Causal Graph Learning for Drug Target Discovery
David Scott Lewis, Enrique Zueco
Drug DiscoveryTarget Identification
AAAI-26 · LMReasoning ↗ ORAL
Neuro-Symbolic AI for Alzheimer's: Physics-Informed Biomarker Prediction
David Scott Lewis, Enrique Zueco
Alzheimer'sBiomarkers
AI4X-AC ↗ ORAL
Brain Resilience Modeling via Physics-Informed Neural Networks
David Scott Lewis, Enrique Zueco
Biomedical AIBrain Resilience
AI4X-AC ↗
Multi-Scale Toxicity Screening via Verified Agentic Pipelines for Pre-Clinical Safety
David Scott Lewis, Enrique Zueco
ToxicologyRegulatory Safety
2025 3 papers
NeurIPS AI4D3 ↗ POSTER
Active Causal Hypothesis Testing for AI-Guided Drug Target Discovery
David Scott Lewis, Enrique Zueco
Drug DiscoveryCausal Models
IROS 2025 ↗ INVITED
Building a Robot Scientist: From Reasoning to Autonomous Discovery
David Scott Lewis, Enrique Zueco
Biomedical AILaboratory Automation

Accelerating Biomedical Insight

Our research is grounded in real-world biological complexity. Contact us to learn how our validated methods can support your therapeutic pipeline.

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